简历：

黄晓蓓，副研究员，工学博士学位。2017年博士毕业于四川大学生物医学工程专业。澳门大学博士后。

1. 开发可用于生物医药领域的新型高分子材料，主要研究方向为肿瘤的靶向药物递送治疗纳米粒的制备，核酸药物的递送高分子材料的制备。
2. 对材料进行表面修饰，使其达到更优的生物相容性与所需性能。例如通过用新型高分子制备三维支架材料，可以更好的促进细胞增殖分化，并为细胞提供生长支持，最终达到形成类器官的目的。目前以第一作者（共一）或通讯作者（共通）在Journal of Controlled Release、Acta Biomaterialia、ACS Macro Letters、Chemical Communications等顶级期刊发表学术论文10余篇。主持或参与国家自然科学基金、重庆市自然科学基金等科研项目10余项。

研究方向：

生物医用高分子 药物靶向递送 药物控制释放

论文和专利情况（论文/著作名称、发表刊物/出版单位名称、发表年份、本人排名）

1. Xiaobei Huang,*, Ning Mu , Yuanfu Ding, Rong Huang, Wei Wu,* , Li Li a,* , Tunan Chen,*. Tumor microenvironment targeting for glioblastoma multiforme treatment via hybrid cell membrane coating supramolecular micelles. Journal of Controlled Release. 2024 (336), 194-203.

2. Jiahao Shi, Bin Ma, Yuhe Zhang, Haiyang Yong, Zhili Li, Sigen A*, Xiaobei Huang*, and Dezhong Zhou*. Targeted Delivery of Anticancer Therapeutics with Polymers by Harnessing Tumor Microenvironment Acidity. Chemistry of Materials. 2023, 35 (17), 6573-6590.

3. Xiaobei Huang, Ning Mu, Yuanfu Ding, Hou Wang Lam, Ludan Yue, Cheng Gao, Tunan Chen,* ZhenYuan* and Ruibing Wang*, Targeted delivery and enhanced uptake of chemo-photodynamic nanomedicine for melanoma treatment. Acta Biomaterialia. 2022, 147, 356-365.

4. Xiaobei Huang,‡ Tunan Chen,‡ Ning Mu, Hou Wang Lam, Chen Sun, Ludan Yue, Qian Cheng, ChengGao, Zhen Yuan* and Ruibing Wang*, Supramolecular micelles as multifunctional theranostic agents for synergistic photodynamic therapy and hypoxia-activated chemotherapy. Acta Biomaterialia. 2021, 131, 483-492.

5. Chenfei Wang, ‡ Xiaobei Huang, ‡ Litao Sun, Qiuxia Li, ZhiliLi, Haiyang Yong, Delu Che, Cong Yan, Songmei Geng,*Wenxin Wang and Dezhong Zhou*, Cyclic poly(ß-amino ester)s with enhanced gene transfection activity synthesized through intra-molecular cyclization. Chemical Communications. 2022, DOI: 10.1039/d1cc06480k.

6. Qiuxia Li, ‡ Litao Sun, ‡ Xiaobei Huang,‡ Shuai Liu,* Haiyang Yong, Chenfei Wang, Jianzhong Li,* and

Dezhong Zhou*, Genetic Engineering of Adipose-Derived Stem Cells Using Biodegradable and Lipid-Like

Highly Branched Poly(β-amino ester)s. ACS Macro Letters. 2022, 11, 636-642.

7. Xiaobei Huang, Ming Zeng, Fatma Alshehri, Xiaolin Li, Jonathan O’ Keeffe-Ahern, Luca Pierucci, Udo, Greiser, Dezhong Zhou, * Guangfu Yin, * Wenxin Wang*, Star poly(β-amino esters) from the combination of linear poly(β-amino esters) and polyethyleneimine. ACS Macro Letters. 2017, 6, 575−579.

8. Xiaobei Huang, Sigen A, Yongsheng Gao, Xiaolin Li, Qian Xu, Xi Wang, Udo, Greiser, Dezhong Zhou, * Guangfu Yin, * Star Polymers from Single-Chain Cyclized/Knotted Nanoparticles as Core. Macromolecular Chemistry and Physics. 2017, 1700473.

9. Xiaobei Huang, Yanzhi Zhang, Guangfu Yin, Ximing Pu , Xiaoming Liao, Zhongbing Huang, Xianchun

Chen, Yadong Yao, Tumor-targeted paclitaxel-loaded folate conjugated poly (ethylene glycol)-poly (L-lactide)

microparticles produced by supercritical fluid technology, Journal of Materials Science: Materials in Medicine. 2015; 26:95.

10. Na Xu, Xiaobei Huang, Guangfu Yin*, Meijiao Bu, Ximing Pu, Xianchun Chen, Xiaoming Liao, Zhongbing Huang, Thermosensitive star polymer pompons with a core-arm structure as thermo-responsive controlled release drug carriers. Rsc Advances 8.28(2018):15604- 15612.

11. Dezhong Zhou, Yongsheng Gao, Jonathan O’Keeffe Ahern, Sigen A, Qian Xu, Xiaobei Huang, ?Udo Greiser, and Wenxin Wang *, Development of Branched Poly(5-Amino-1-pentanol-co-1,4-butanediol Diacrylate) with High Gene Transfection Potency Across Diverse Cell Types. Acs Applied Materials & Interfaces, 2016,

8(50):34218-34226.

12. Dezhong Zhou, Luca Pierucci, Yongsheng Gao, Jonathan O’Keeffe Ahern, Xiaobei Huang, A. Sigen, and Wenxin Wang*, Thermo- and pH-Responsive, Coacervate-Forming Hyperbranched Poly(β-amino ester)s for Selective Cell Binding'. ACS APPLIED MATERIALS & INTERFACES, 2017, 9(7), 5793-5802.

专利：

1. 黄晓蓓，穆宁；一种以氨基聚乙二醇为凝胶基质的抗菌凝胶的制备方法，2024-03-25，中国，202111563211.2。
2. 穆宁，黄晓蓓；一种以聚乙烯亚胺为凝胶基质的抗菌凝胶的制备方法, 2022-11-18, 中国，CN202111562037.X。